Brittle Bone Drug Could Help Treat Hair Loss, Researchers Say

Faith Castro
May 10, 2018

Baldness could be beaten by an experimental drug originally created to treat brittle bone disease, research suggests.

According to researchers from The University of Manchester's Centre for Dermatology Research, a new drug - originally created to treat osteoporosis - could help men and women suffering from baldness.

"Clearly though, a clinical trial is required next to tell us whether this drug or similar compounds are both effective and safe in hair loss patients", he added.

There are now two drugs available to treat balding - minoxidil (for men and women) and finasteride (for men) - but both have side-effects and are not always effective. Currently, the only two drugs available for treatment of male-pattern balding known as androgenetic alopecia have moderate side effects and often produce disappointing hair regrowth results, says the Manchester study.

The team's experiments revealed that CsA curbs SFRP1, a protein that keeps various tissues like hair follicles from growing and developing.

The drug was actually originally created to treat transplant patients, to suppress transplant rejection and autoimmune diseases.

The findings appear in the journal PLOS Biology.

Scientists found the therapy promotes speedy sprouting of hair in lab tests.

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But because of its side effects, CsA was unsuitable as a baldness treatment.

This medication, Cyclosporine A (CsA), has been commonly used as the 1980s to curb transplant rejection and autoimmune illnesses.

A study conducted by the University of Manchester's Center for Dermatology Research found that a compound in the medicine could stop the effects of a protein that is suppressing hair growth in the follicles, USA Today reports.

Baldness can be dealt with an experimental drug that was primarily developed to deal with a condition that undermines the bones after hopeful indications that it can cause the follicles to grow new hair.

While you wait for a surefire solution to hair loss, consider embracing your baldness.

There is a third option of a hair transplant, but this can be costly and out of reach for many men.

However, CaA's severe side effects other than a boost in hair growth make it an unappealing choice. The research concludes the active switching of the hair follicles to the hair growth phase.

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